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Yoshitaka Ohkubo Selected Research

3- (difluoromethyl)- 1- (4- methoxyphenyl)- 5- (4- (methylsulfinyl)phenyl)pyrazole

10/2003Effect of systemic FR140423, a new analgesic compound, in a rat model of postoperative pain: contribution of delta-opioid receptors.
9/2003Role of cyclooxygenase-2, but not cyclooxygenase-1, on type II collagen-induced arthritis in DBA/1J mice.

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Yoshitaka Ohkubo Research Topics

Disease

6Inflammation (Inflammations)
07/2005 - 07/2003
5Arthritis (Polyarthritis)
01/2005 - 07/2003
4Experimental Arthritis
10/2011 - 06/2004
4Hyperalgesia
10/2011 - 07/2003
4Rheumatoid Arthritis
07/2005 - 07/2003
3Pain (Aches)
07/2005 - 10/2002
2Edema (Dropsy)
10/2011 - 09/2003
2Dermatitis
01/2004 - 12/2002
1Acute Lung Injury
05/2005
1Eosinophilia
04/2005
1Body Weight (Weight, Body)
01/2005
1Atopic Dermatitis (Atopic Eczema)
01/2004
1Postoperative Pain
10/2003
1Allergic Rhinitis
04/2003
1Asthma (Bronchial Asthma)
04/2003
1Allergic Contact Dermatitis
12/2002
1Psoriasis (Pustulosis Palmaris et Plantaris)
12/2002
1Hyperplasia
12/2002

Drug/Important Bio-Agent (IBA)

8Tacrolimus (Prograf)FDA LinkGeneric
07/2005 - 12/2002
6Pharmaceutical PreparationsIBA
07/2005 - 04/2003
2Prostaglandins EIBA
07/2005 - 09/2003
2AntigensIBA
04/2005 - 01/2004
2Methotrexate (Mexate)FDA LinkGeneric
03/2005 - 10/2003
2Matrix Metalloproteinase InhibitorsIBA
01/2005 - 01/2005
2Matrix Metalloproteinases (MMPs)IBA
01/2005 - 01/2005
2Collagen Type II (Type II Collagen)IBA
06/2004 - 09/2003
2pyrazoleIBA
10/2003 - 09/2003
23- (difluoromethyl)- 1- (4- methoxyphenyl)- 5- (4- (methylsulfinyl)phenyl)pyrazoleIBA
10/2003 - 09/2003
2Analgesics (Analgesic Drugs)IBA
10/2003 - 07/2003
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2003 - 07/2003
1CarrageenanIBA
10/2011
1rofecoxib (Vioxx)FDA Link
10/2011
1Acetic Acid (Vinegar)FDA LinkGeneric
10/2011
1Diclofenac (SR 38)FDA LinkGeneric
10/2011
1Dexamethasone (Maxidex)FDA LinkGeneric
05/2005
1Bleomycin (Blenoxane)FDA LinkGeneric
05/2005
1AlbuminsIBA
04/2005
1AerosolsIBA
04/2005
1Tartrate-Resistant Acid PhosphataseIBA
01/2005
1FR217840IBA
01/2005
1pyridinolineIBA
01/2005
1Collagenases (Collagenase)FDA Link
01/2005
1GelatinasesIBA
01/2005
1FR255031IBA
01/2005
1Biomarkers (Surrogate Marker)IBA
06/2004
1collagen type I trimeric cross-linked peptideIBA
06/2004
1Ointments (Pastes)IBA
01/2004
1Opioid Analgesics (Opioids)IBA
10/2003
1naloxonazineIBA
10/2003
1naltrindoleIBA
10/2003
1Morphine (MS Contin)FDA LinkGeneric
10/2003
1Naloxone (Narcan)FDA LinkGeneric
10/2003
1Narcotic Antagonists (Opioid Antagonists)IBA
10/2003
1delta Opioid Receptors (delta Opioid Receptor)IBA
10/2003
1Interleukin-6 (Interleukin 6)IBA
10/2003
1InterleukinsIBA
10/2003
1CytokinesIBA
10/2003
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
09/2003
1ThromboxanesIBA
09/2003
1Arachidonic Acid (Vitamin F)IBA
09/2003
1Indomethacin (Indometacin)FDA LinkGeneric
09/2003
1Protein Isoforms (Isoforms)IBA
09/2003
1Cyclooxygenase 1IBA
09/2003
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
09/2003
12,5-dichloro-4-bromophenol (B 2)IBA
09/2003
1ProstaglandinsIBA
09/2003
1Calcineurin InhibitorsIBA
07/2003
1FR 173657IBA
04/2003
1Interferon-gamma (Interferon, gamma)IBA
12/2002
1OxazoloneIBA
12/2002
11- (4- fluorophenyl)- 3- methyl- 5- (4- (methylsulfinyl)phenyl)pyrazoleIBA
10/2002

Therapy/Procedure

3Oral Administration
01/2005 - 09/2003
1Topical Administration
12/2002